Antidiarrheal efficacy and cellular mechanisms of a Thai herbal remedy.

Screening of herbal remedies for Cl(-) channel inhibition identified Krisanaklan, a herbal extract used in Thailand for treatment of diarrhea, as an effective antidiarrheal in mouse models of secretory diarrheas with inhibition activity against three Cl(-) channel targets. Krisanaklan fully inhibite...

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Bibliographic Details
Main Authors: Lukmanee Tradtrantip, Eun-A Ko, Alan S Verkman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3923670?pdf=render