Autologous blood transfusion augments impaired wound healing in diabetic mice by enhancing lncRNA H19 expression via the HIF-1α signaling pathway

Autologous blood transfusion augments impaired wound healing in diabetic mice by enhancing lncRNA H19 expression via the HIF-1α signaling pathway

Abstract Background Impaired wound healing frequently occurs in diabetes mellitus (DM) and is implicated in impaired angiogenesis. Long non-coding RNA (lncRNA) H19 has been reported as being reduced in DM and played a critical role in inducing angiogenesis. Thus, we hypothesized that H19 may affect...

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Bibliographic Details
Main Authors: Jian-Rong Guo, Lei Yin, Yong-Quan Chen, Xiao-Ju Jin, Xun Zhou, Na-Na Zhu, Xiao-Qian Liu, Han-Wei Wei, Li-Shuang Duan
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Cell Communication and Signaling
Subjects:
Long non-coding RNA H19
EZH2
HIF-1α signaling pathway
Modified autologous blood
Fibroblast activation
Histone methylation
Online Access:http://link.springer.com/article/10.1186/s12964-018-0290-6

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http://link.springer.com/article/10.1186/s12964-018-0290-6

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