Differentiation of adipose-derived stem cells to functional CD105neg CD73low melanocyte precursors guided by defined culture condition

Differentiation of adipose-derived stem cells to functional CD105neg CD73low melanocyte precursors guided by defined culture condition

Abstract Background The generation of functional human epidermal melanocytes (HEM) from stem cells provides an unprecedented source for cell-based therapy in vitiligo. Despite the important efforts exerted to obtain melanin-producing cells from stem cells, pre-clinical results still lack the safety...

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Bibliographic Details
Main Authors: Gabriela Zavala, Carolina Sandoval, Daniel Meza, Rafael Contreras, Walter Gubelin, Maroun Khoury
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Stem Cell Research & Therapy
Subjects:
Melanocytes
ADSC
Vitiligo
Differentiation
MITF
Tyrosinase
Online Access:http://link.springer.com/article/10.1186/s13287-019-1364-0

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http://link.springer.com/article/10.1186/s13287-019-1364-0

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