Predicting T cell recognition of MHC class I restricted neoepitopes

Predicting T cell recognition of MHC class I restricted neoepitopes

Epitopes that arise from a somatic mutation, also called neoepitopes, are now known to play a key role in cancer immunology and immunotherapy. Recent advances in high-throughput sequencing have made it possible to identify all mutations and thereby all potential neoepitope candidates in an individua...

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Bibliographic Details
Main Authors: Zeynep Koşaloğlu-Yalçın, Manasa Lanka, Angela Frentzen, Ashmitaa Logandha Ramamoorthy Premlal, John Sidney, Kerrie Vaughan, Jason Greenbaum, Paul Robbins, Jared Gartner, Alessandro Sette, Bjoern Peters
Format: Article
Language:English
Published: Taylor & Francis Group 2018-11-01
Series:OncoImmunology
Subjects:
cancer
immunotherapy
neoepitope
neoantigen
hla binding
bioinformatics
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1492508

Internet

http://dx.doi.org/10.1080/2162402X.2018.1492508

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