Thrombotic microangiopathy and liver toxicity due to a combination therapy of leflunomide and methotrexate: a case report

Abstract Background Treatment of active rheumatoid arthritis may necessitate a methotrexate mono- or combination therapy. As in the present case, novel side effects may occur, when escalating therapy. Case presentation A 63-year-old Caucasian female patient with rheumatoid arthritis on methotrexate...

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Bibliographic Details
Main Authors: Rainer Ullrich Pliquett, Christoph Lübbert, Christoph Schäfer, Matthias Girndt
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Medical Case Reports
Subjects:
Online Access:https://doi.org/10.1186/s13256-020-2349-4