Metformin Inhibits the Urea Cycle and Reduces Putrescine Generation in Colorectal Cancer Cell Lines
The urea cycle (UC) removes the excess nitrogen and ammonia generated by nitrogen-containing compound composites or protein breakdown in the human body. Research has shown that changes in UC enzymes are not only related to tumorigenesis and tumor development but also associated with poor survival in...
Main Authors: | Tao Zhang, Ling Hu, Jia-Feng Tang, Hang Xu, Kuan Tian, Meng-Na Wu, Shi-Ying Huang, Yu-Mei Du, Peng Zhou, Rui-Jin Lu, Shuang He, Jia-Mei Xu, Jian-Jun Si, Jing Li, Di-Long Chen, Jian-Hua Ran |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/26/7/1990 |
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