Effective cardiac myocyte differentiation of human induced pluripotent stem cells requires VEGF.

Perhaps one of the most significant achievements in modern science is the discovery of human induced pluripotent stem cells (hiPSCs), which have paved the way for regeneration therapy using patients' own cells. Cardiomyocytes differentiated from hiPSCs (hiPSC-CMs) could be used for modelling pa...

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Bibliographic Details
Main Authors: Lei Ye, Sophia Zhang, Lucas Greder, James Dutton, Susan A Keirstead, Mike Lepley, Liying Zhang, Dan Kaufman, Jianyi Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3542360?pdf=render