Gestational exposure to PM2.5 leads to cognitive dysfunction in mice offspring via promoting HMGB1-NLRP3 axis mediated hippocampal inflammation

Gestational exposure to PM2.5 leads to cognitive dysfunction in mice offspring via promoting HMGB1-NLRP3 axis mediated hippocampal inflammation

PM2.5 is recently identified as a kind of material possessing severe biohazard. It can enter human body and exerts pathological effects on lung, eyes, and the central nervous system (CNS). Maternal exposure to PM2.5 can affect neural development and cause cognitive decline in offspring, with the und...

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Bibliographic Details
Main Authors: Tianliang Zhang, Lijuan Sun, Tingting Wang, Chong Liu, Haoyun Zhang, Can Zhang, Li Yu
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Cognitive impairment
Inflammasome
Inflammatory response
Neuroinflammation
Microglia activation
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321007296

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http://www.sciencedirect.com/science/article/pii/S0147651321007296

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