Regulation of Mitochondrial Respiratory Chain Complex Levels, Organization, and Function by Arginyltransferase 1

Regulation of Mitochondrial Respiratory Chain Complex Levels, Organization, and Function by Arginyltransferase 1

Arginyltransferase 1 (ATE1) is an evolutionary-conserved eukaryotic protein that localizes to the cytosol and nucleus. It is the only known enzyme in metazoans and fungi that catalyzes posttranslational arginylation. Lack of arginylation has been linked to an array of human disorders, including canc...

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Bibliographic Details
Main Authors: Chunhua Jiang, Balaji T. Moorthy, Devang M. Patel, Akhilesh Kumar, William M. Morgan, Belkis Alfonso, Jingyu Huang, Theodore J. Lampidis, Daniel G. Isom, Antoni Barrientos, Flavia Fontanesi, Fangliang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
arginylation
arginyltransferase
mitochondria
biogenesis
respiration
respiratory chain complexes
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.603688/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.603688/full

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