Determination of the optimal dose of ephedrine in the treatment of arterial hypotension due to general anesthesia in neonates and infants below 6 months old: the ephedrine study protocol for a randomized, open-label, controlled, dose escalation trial

Abstract Background Arterial hypotension induced by general anesthesia is commonly identified as a risk factor of morbidity, especially neurological, after cardiac or noncardiac surgery in adults and children. Intraoperative hypotension is observed with sevoflurane anesthesia in children, in particu...

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Main Authors: A. S. Szostek, P. Boucher, F. Subtil, O. Zerzaihi, C. Saunier, M. de Queiroz Siqueira, F. Merquiol, P. Martin, M. Granier, A. Gerst, A. Lambert, T. Storme, D. Chassard, P. Nony, B. Kassai, S. Gaillard
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-021-05155-2