Generation of the Niemann–Pick type C2 patient-derived iPSC line AKOSi001-A

Generation of the Niemann–Pick type C2 patient-derived iPSC line AKOSi001-A

Niemann-Pick disease Type C (NPC) is a rare progressive neurodegenerative disorder with an incidence of 1:120,000 caused by mutations in the NPC1 or NPC2 gene. Only 5% of NPC patients suffer from mutations of the NPC2 gene. Here we demonstrate the generation of a Niemann–Pick disease Type C2 (NPC2)...

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Bibliographic Details
Main Authors: Christin Völkner, Franziska Peter, Maik Liedtke, Saskia Krohn, Iris Lindner, Hugo Murua Escobar, Chiara Cimmaruta, Jan Lukas, Andreas Hermann, Moritz J. Frech
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506119302363

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http://www.sciencedirect.com/science/article/pii/S1873506119302363

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