Recovery of Recombinant Crimean Congo Hemorrhagic Fever Virus Reveals a Function for Non-structural Glycoproteins Cleavage by Furin.

Recovery of Recombinant Crimean Congo Hemorrhagic Fever Virus Reveals a Function for Non-structural Glycoproteins Cleavage by Furin.

Crimean Congo hemorrhagic fever virus (CCHFV) is a negative-strand RNA virus of the family Bunyaviridae (genus: Nairovirus). In humans, CCHFV causes fever, hemorrhage, severe thrombocytopenia, and high fatality. A major impediment in precisely determining the basis of CCHFV's high pathogenicity...

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Bibliographic Details
Main Authors: Éric Bergeron, Marko Zivcec, Ayan K Chakrabarti, Stuart T Nichol, César G Albariño, Christina F Spiropoulou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4416775?pdf=render

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http://europepmc.org/articles/PMC4416775?pdf=render

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