Impaired Nicotinamide Adenine Dinucleotide Biosynthesis in the Kidney of Chronic Kidney Disease

Impaired Nicotinamide Adenine Dinucleotide Biosynthesis in the Kidney of Chronic Kidney Disease

Chronic kidney disease (CKD) is a global public health problem with high morbidity and mortality. Decreased nicotinamide adenine dinucleotide (NAD+) levels were found to be associated with aging, cancer, and neurodegenerative and metabolic disorders. However, the alteration of renal NAD+ levels and...

Full description

Bibliographic Details
Main Authors: Xinhui Liu, Denggui Luo, Shiying Huang, Siqi Liu, Bing Zhang, Fochang Wang, Jiandong Lu, Jianping Chen, Shunmin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Physiology
Subjects:
chronic kidney disease
nicotinamide adenine dinucleotide
the de novo pathway
the salvage pathway
the Preiss-Handler pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.723690/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.723690/full

Similar Items