Heparan Sulfate Mediates Neuroprotection from Degeneration in Experimental Glutaric Aciduria

Glutaric aciduria type 1 (GA1) is a childhood metabolic disorder associated with crises that lead to striatal necrosis. Although the disorder can be controlled with diet, there is no current treatment to ameliorate the neurodegeneration following a metabolic crisis. We hypothesized that heparan sulf...

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Bibliographic Details
Main Authors: Michelle C. Naylor, Mesfin Negia, Meredith Noetzel, Terry C. Burns, Zach L. Demorest, Walter C. Low Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2007-03-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000007783464786