Closed-loop neural stimulation for pentylenetetrazole-induced seizures in zebrafish

SUMMARY Neural stimulation can reduce the frequency of seizures in persons with epilepsy, but rates of seizure-free outcome are low. Vagus nerve stimulation prevents seizures by continuously activating noradrenergic projections from the brainstem to the cortex. Cortical norepinephrine then increases...

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Bibliographic Details
Main Authors: Ricardo Pineda, Christine E. Beattie, Charles W. Hall
Format: Article
Language:English
Published: The Company of Biologists 2013-01-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/6/1/64