Dynamin-Related Protein 1-Dependent Mitochondrial Fission Changes in the Dorsal Vagal Complex Regulate Insulin Action

Dynamin-Related Protein 1-Dependent Mitochondrial Fission Changes in the Dorsal Vagal Complex Regulate Insulin Action

Mitochondria undergo dynamic changes to maintain function in eukaryotic cells. Insulin action in parallel regulates glucose homeostasis, but whether specific changes in mitochondrial dynamics alter insulin action and glucose homeostasis remains elusive. Here, we report that high-fat feeding in roden...

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Bibliographic Details
Main Authors: Beatrice M. Filippi, Mona A. Abraham, Pamuditha N. Silva, Mozhgan Rasti, Mary P. LaPierre, Paige V. Bauer, Jonathan V. Rocheleau, Tony K.T. Lam
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Cell Reports
Subjects:
dorsal vagal complex
dynamin-related protein 1
mitochondrial fission
insulin resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717302164

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http://www.sciencedirect.com/science/article/pii/S2211124717302164

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