AUNIP/C1orf135 directs DNA double-strand breaks towards the homologous recombination repair pathway

AUNIP/C1orf135 directs DNA double-strand breaks towards the homologous recombination repair pathway

DNA double strand breaks can be repaired by homology-independent or homology-directed mechanisms. The choice between these pathways is a key event for genomic stability maintenance. Here the authors identify and characterize AUNIP, as a factor involved in tilting the balance towards homology repair.

Bibliographic Details
Main Authors: Jiangman Lou, Hongxia Chen, Jinhua Han, Hanqing He, Michael S. Y. Huen, Xin-hua Feng, Ting Liu, Jun Huang
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01151-w

Internet

https://doi.org/10.1038/s41467-017-01151-w

Similar Items