Evolutionarily significant A-to-I RNA editing events originated through G-to-A mutations in primates

Evolutionarily significant A-to-I RNA editing events originated through G-to-A mutations in primates

Abstract Background Recent studies have revealed thousands of A-to-I RNA editing events in primates, but the origination and general functions of these events are not well addressed. Results Here, we perform a comparative editome study in human and rhesus macaque and uncover a substantial proportion...

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Bibliographic Details
Main Authors: Ni A. An, Wanqiu Ding, Xin-Zhuang Yang, Jiguang Peng, Bin Z. He, Qing Sunny Shen, Fujian Lu, Aibin He, Yong E. Zhang, Bertrand Chin-Ming Tan, Jia-Yu Chen, Chuan-Yun Li
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Genome Biology
Subjects:
RNA editing
Origination
Primate evolution
G-to-A mutation
Population genetics
Online Access:http://link.springer.com/article/10.1186/s13059-019-1638-y

Internet

http://link.springer.com/article/10.1186/s13059-019-1638-y

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