Acetylation-Dependent Regulation of Notch Signaling in Macrophages by SIRT1 Affects Sepsis Development

Acetylation-Dependent Regulation of Notch Signaling in Macrophages by SIRT1 Affects Sepsis Development

SIRT1 is reported to participate in macrophage differentiation and affect sepsis, and Notch signaling is widely reported to influence inflammation and macrophage activation. However, the specific mechanisms through which SIRT1 regulates sepsis and the relationship between SIRT1 and Notch signaling r...

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Bibliographic Details
Main Authors: Xiaozhi Bai, Ting He, Yang Liu, Julei Zhang, Xiaoqiang Li, Jihong Shi, Kejia Wang, Fu Han, Wei Zhang, Yijie Zhang, Weixia Cai, Dahai Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
sepsis
SIRT1
Notch
macrophage
deacetylate
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00762/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00762/full

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