Immune Checkpoint Inhibition in Hodgkin Lymphoma

Abstract. Intricate systems of checkpoints such as the programmed cell death protein 1 (PD-1)/programmed death ligand 1 (PD-L1) axis regulate adaptive immune responses to protect against tissue damage. However, diverse cancers can exploit these pathways to evade or suppress antitumor immunity, leadi...

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Bibliographic Details
Main Authors: Ryan H. Moy, Anas Younes
Format: Article
Language:English
Published: Wolters Kluwer 2018-02-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000020