The Role of Panx3 in Age-Associated and Injury-Induced Intervertebral Disc Degeneration

The Role of Panx3 in Age-Associated and Injury-Induced Intervertebral Disc Degeneration

Pannexin 3 (Panx3) is a mechanosensitive, channel-forming glycoprotein implicated in the progression of post-traumatic osteoarthritis. Despite evidence for <i>Panx3</i> expression in the intervertebral disc (IVD), its function in this cartilaginous joint structure remained unknown. Using...

Full description

Bibliographic Details
Main Authors: Meaghan Serjeant, Paxton M. Moon, Diana Quinonez, Silvia Penuela, Frank Beier, Cheryle A. Séguin
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
pannexin 3
intervertebral disc degeneration
mechanical stress
needle puncture injury
transgenic mice
Online Access:https://www.mdpi.com/1422-0067/22/3/1080

Internet

https://www.mdpi.com/1422-0067/22/3/1080

Similar Items