Mesenchymal stem cells engineered to inhibit complement-mediated damage.

Mesenchymal stem cells engineered to inhibit complement-mediated damage.

Mesenchymal stem cells (MSC) preferentially migrate to damaged tissues and, due to their immunomodulatory and trophic properties, contribute to tissue repair. Although MSC express molecules, such as membrane cofactor protein (CD46), complement decay-accelerating factor (CD55), and protectin (CD59),...

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Bibliographic Details
Main Authors: Melisa A Soland, Mariana Bego, Evan Colletti, Esmail D Zanjani, Stephen St Jeor, Christopher D Porada, Graça Almeida-Porada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3608620?pdf=render

Internet

http://europepmc.org/articles/PMC3608620?pdf=render

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