Clinical significance of atypical protein kinase C (PKCι and PKCζ) and its relationship with yes-associated protein in lung adenocarcinoma

Clinical significance of atypical protein kinase C (PKCι and PKCζ) and its relationship with yes-associated protein in lung adenocarcinoma

Abstract Background Protein kinase C iota (PKCι) and protein kinase C zeta (PKCζ) are two atypical protein kinase (aPKC) enzymes that contribute to cell proliferation and cancer development. The Hippo/YAP pathway is commonly disrupted and upregulated in cancers. Herein, the expression patterns and c...

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Bibliographic Details
Main Authors: Kyung-Hee Kim, Chaeuk Chung, Jin-Man Kim, Dahye Lee, Sang Yeon Cho, Tae Hee Lee, Hyun Jin Cho, Min-Kyung Yeo
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Cancer
Subjects:
Atypical protein kinase C
Protein kinase C iota
Protein kinase C zeta
Lung adenocarcinoma
Online Access:http://link.springer.com/article/10.1186/s12885-019-5992-7

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http://link.springer.com/article/10.1186/s12885-019-5992-7

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