Circulating MicroRNAs Regulating DNA Damage Response and Responsiveness to Cisplatin in the Prognosis of Patients with Non-Small Cell Lung Cancer Treated with First-Line Platinum Chemotherapy

Circulating MicroRNAs Regulating DNA Damage Response and Responsiveness to Cisplatin in the Prognosis of Patients with Non-Small Cell Lung Cancer Treated with First-Line Platinum Chemotherapy

The expression of microRNA (miR)-21, miR-128, miR-155, and miR-181a involved in DNA damage response (DDR) and tumor responsiveness to platinum was assessed by RT-qPCR in the plasma of patients with non-small cell lung cancer (NSCLC; n = 128) obtained prior to initiation of first-line platinum chemot...

Full description

Bibliographic Details
Main Authors: Chara Papadaki, Alexia Monastirioti, Konstantinos Rounis, Dimitrios Makrakis, Konstantinos Kalbakis, Christofors Nikolaou, Dimitrios Mavroudis, Sofia Agelaki
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
circulating miRNAs
NSCLC
platinum-based chemotherapy
DNA damage response
hypoxia
Online Access:https://www.mdpi.com/2072-6694/12/5/1282

Internet

https://www.mdpi.com/2072-6694/12/5/1282

Similar Items