An optimized approach for local de novo assembly of overlapping paired-end RAD reads from multiple individuals

An optimized approach for local de novo assembly of overlapping paired-end RAD reads from multiple individuals

Restriction site-associated DNA (RAD) sequencing is revolutionizing studies in ecological, evolutionary and conservation genomics. However, the assembly of paired-end RAD reads with random-sheared ends is still challenging, especially for non-model species with high genetic variance. Here, we presen...

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Bibliographic Details
Main Authors: Yu-Long Li, Dong-Xiu Xue, Bai-Dong Zhang, Jin-Xian Liu
Format: Article
Language:English
Published: The Royal Society 2018-01-01
Series:Royal Society Open Science
Subjects:
overlapping paired-end sequencing
rad-seq
optimized assembly
pipeline software
optimal clustering
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.171589

Internet

https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.171589

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