Susceptibility of lung epithelium to neutrophil elastase: protection by native inhibitors

The development of emphysema is thought to be due to an imbalance of proteases (especially neutrophil elastase [NE]) and antiproteases with loosening of the respiratory epithelium as an early event. We investigated the effect of NE on respiratory epithelial cell adherence in vitro , in the presence...

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Bibliographic Details
Main Authors: L. Bingle, R. J. Richards, B. Fox, L. Masek, A. Guz, T. D. Tetley
Format: Article
Language:English
Published: Hindawi Limited 1997-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629359791488