Application of Box–Behnken design and desirability function in the development and optimization of self-nanoemulsifying drug delivery system for enhanced dissolution of ezetimibe

Application of Box–Behnken design and desirability function in the development and optimization of self-nanoemulsifying drug delivery system for enhanced dissolution of ezetimibe

Abstract Background This study is focused on developing and optimizing a self-nanoemulsifying drug delivery system (SNEDDS) of BCS class II drug (ezetimibe) through Box–Behnken design (BBD) and desirability function for enhanced dissolution. Pseudoternary phase diagrams were created by taking oil (P...

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Bibliographic Details
Main Authors: Pragya Yadav, Vaibhav Rastogi, Anurag Verma
Format: Article
Language:English
Published: SpringerOpen 2020-03-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
SNEDDS
BCS
Box–Behnken design
Ezetimibe
Desirability function
Optimization
Online Access:http://link.springer.com/article/10.1186/s43094-020-00023-3

Internet

http://link.springer.com/article/10.1186/s43094-020-00023-3

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