Inactivated Orf-virus shows disease modifying antiviral activity in a guinea pig model of genital herpesvirus infection

Background: Inactivated Orf virus (iORFV) has been used as a preventative as well as a therapeutic immunomodulator in veterinary medicine in different species. iORFV elicits strong effects on cytokine secretion in mice and human immune cells leading to an auto-regulated loop of initial up-regulation...

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Bibliographic Details
Main Authors: Astrid Friebe, Angela Siegling, Olaf Weber
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Journal of Microbiology, Immunology and Infection
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118217300786