Increased P2×2 receptors induced by amyloid-β peptide participates in the neurotoxicity in alzheimer’s disease

Increased P2×2 receptors induced by amyloid-β peptide participates in the neurotoxicity in alzheimer’s disease

Amyloid beta peptide (Aβ) is tightly associated with the physiopathology of Alzheimer’s Disease (AD) as one of the most important factors in the evolution of the pathology. In this context, we previously reported that Aβ increases the expression of ionotropic purinergic receptor 2 (P2×2R). However,...

Full description

Bibliographic Details
Main Authors: Pamela A. Godoy, Daniela Mennickent, Inmaculada Cuchillo-Ibáñez, Oscar Ramírez-Molina, Tiare Silva-Grecchi, Jessica Panes-Fernández, Patricio Castro, Javier Sáez-Valero, Jorge Fuentealba
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
P2×2
Purinergic receptors
Amyloid beta
Alzheimer’s disease
Fe65
APP
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221007502

Internet

http://www.sciencedirect.com/science/article/pii/S0753332221007502

Similar Items