Linear population allocation by bistable switches in response to transient stimulation.

Many cellular decision processes, including proliferation, differentiation, and phenotypic switching, are controlled by bistable signaling networks. In response to transient or intermediate input signals, these networks allocate a population fraction to each of two distinct states (e.g. OFF and ON)....

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Bibliographic Details
Main Authors: Jaydeep K Srimani, Guang Yao, John Neu, Yu Tanouchi, Tae Jun Lee, Lingchong You
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4139379?pdf=render