The Flick of a Switch: Conferring Survival Advantage to Breast Cancer Stem Cells Through Metabolic Plasticity

The Flick of a Switch: Conferring Survival Advantage to Breast Cancer Stem Cells Through Metabolic Plasticity

Within heterogeneous tumors, cancer stem cell (CSC) populations exhibit the greatest tumor initiation potential, promote metastasis, and contribute to therapy resistance. For breast cancer specifically, CSCs are identified by CD44highCD24low cell surface marker expression and increased aldehyde dehy...

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Bibliographic Details
Main Authors: Hayley R. Walsh, Brianne M. Cruickshank, Justin M. Brown, Paola Marcato
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Oncology
Subjects:
breast cancer
metabolic plasticity
CSCs
incRNAs
miRNAs
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00753/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00753/full

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