Dysregulation of PAK1 Is Associated with DNA Damage and Is of Prognostic Importance in Primary Esophageal Small Cell Carcinoma

Primary esophageal small cell carcinoma (PESCC) is a rare, but fatal subtype of esophageal carcinoma. No effective therapeutic regimen for it. P21-activated kinase 1 (PAK1) is known to function as an integrator and an indispensable node of major growth factor signaling and the molecular therapy targ...

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Bibliographic Details
Main Authors: Jinfeng Gan, Yuling Zhang, Xiurong Ke, Chong Tan, Hongzheng Ren, Hongmei Dong, Jiali Jiang, Shaobin Chen, Yixuan Zhuang, Hao Zhang
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/16/6/12035