Clinicopathological significance and prognostic value of lactate dehydrogenase A expression in gastric cancer patients.

INTRODUCTION: LDH-A, the enzyme responsible for transforming pyruvate into lactate, has been demonstrated to be up-regulated in many types of cancer and to give rise to more aggressive behavior by regulating proliferation and anti-apoptosis. However, its expression in gastric cancer (GC) has not bee...

Full description

Bibliographic Details
Main Authors: Xuren Sun, Zhe Sun, Zhi Zhu, Haixia Guan, Junyan Zhang, Yining Zhang, Huimian Xu, Mingjun Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3946663?pdf=render