Studies on the biosynthesis of cholesterol: XII. synthesis of allyl pyrophosphates from mevalonate and their conversion into squalene with liver enzymes*
The biosynthesis of allyl pyrophosphates (the pyrophosphates of dimethylallyl alcohol, geraniol, and of farnesol) from dl-mevalonate-2-C14 and from (-)5-phosphomevalonate-2-C14 with soluble liver enzymes in the presence of ATP and Mg++ is described. The allyl pyrophosphates were partially purified a...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1960-07-01
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| Series: | Journal of Lipid Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520390507 |