Regulation of PD-L1 Expression by NF-κB in Cancer

Regulation of PD-L1 Expression by NF-κB in Cancer

Immune checkpoints are inhibitory receptor/ligand pairs regulating immunity that are exploited as key targets of anti-cancer therapy. Although the PD-1/PD-L1 pair is one of the most studied immune checkpoints, several aspects of its biology remain to be clarified. It has been established that PD-1 i...

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Bibliographic Details
Main Authors: Fabrizio Antonangeli, Ambra Natalini, Marina Chiara Garassino, Antonio Sica, Angela Santoni, Francesca Di Rosa
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
tumor associated macrophages
T cells
immune checkpoint inhibitors
tumor immunity
non-small-cell-lung cancer
tissue homeostasis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.584626/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2020.584626/full

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