Potential excess mortality in BRCA1/2 mutation carriers beyond breast, ovarian, prostate, and pancreatic cancers, and melanoma.

Although the increase in risk of developing breast, ovarian, and prostate cancer in BRCA1 and BRCA2 mutation carriers has been studied extensively, its impact on mortality is not well quantified. Further, possible effect of BRCA mutations on non-cancer mortality risk has not been examined.Using mort...

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Bibliographic Details
Main Authors: Phuong L Mai, Nilanjan Chatterjee, Patricia Hartge, Margaret Tucker, Lawrence Brody, Jeffery P Struewing, Sholom Wacholder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2652075?pdf=render