Assessing the role of surface glycans of extracellular vesicles on cellular uptake

Abstract Extracellular vesicles (EVs) are important mediators of cell-cell communication in a broad variety of physiological contexts. However, there is ambiguity around the fundamental mechanisms by which these effects are transduced, particularly in relation to their uptake by recipient cells. Mul...

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Bibliographic Details
Main Authors: Charles Williams, Raquel Pazos, Félix Royo, Esperanza González, Meritxell Roura-Ferrer, Aitor Martinez, Jorge Gamiz, Niels-Christian Reichardt, Juan M Falcón-Pérez
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-48499-1