Low bone strength is a manifestation of phenylketonuria in mice and is attenuated by a glycomacropeptide diet.

Phenylketonuria (PKU), caused by phenylalanine (phe) hydroxylase loss of function mutations, requires a low-phe diet plus amino acid (AA) formula to prevent cognitive impairment. Glycomacropeptide (GMP), a low-phe whey protein, provides a palatable alternative to AA formula. Skeletal fragility is a...

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Bibliographic Details
Main Authors: Patrick Solverson, Sangita G Murali, Suzanne J Litscher, Robert D Blank, Denise M Ney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3445501?pdf=render