Contribution of NAADP to Glutamate-Evoked Changes in Ca2+ Homeostasis in Mouse Hippocampal Neurons

Contribution of NAADP to Glutamate-Evoked Changes in Ca2+ Homeostasis in Mouse Hippocampal Neurons

Nicotinic acid adenine dinucleotide phosphate (NAADP) is a second messenger that evokes calcium release from intracellular organelles by the engagement of calcium release channels, including members of the Transient Receptor Potential (TRP) family, such as TRPML1, the (structurally) related Two Pore...

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Bibliographic Details
Main Authors: Julia Hermann, Melanie Bender, Dagmar Schumacher, Marcel S. Woo, Artem Shaposhnykov, Sina C. Rosenkranz, Vladimir Kuryshev, Chris Meier, Andreas H. Guse, Manuel A. Friese, Marc Freichel, Volodymyr Tsvilovskyy
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
hippocampal neurons
glutamate
NAADP
Ca2+ homeostasis
neuronal excitotoxicity
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00496/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00496/full

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