H3.3 kinetics predicts chromatin compaction status of parental genomes in early embryos
Abstract Background After fertilization, the fusion of gametes results in the formation of totipotent zygote. During sperm-egg fusion, maternal factors participate in parental chromatin remodeling. H3.3 is a histone H3 variant that plays essential roles in mouse embryogenesis. Methods Here, we used...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-06-01
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Series: | Reproductive Biology and Endocrinology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12958-021-00776-3 |