Ethanol extracts of Allium sp. regulate cyclooxygenase-2 and E-cadherin expression in gastric cancer MKN74 cell line and enhance doxorubicin toxicity

Ethanol extracts of Allium sp. regulate cyclooxygenase-2 and E-cadherin expression in gastric cancer MKN74 cell line and enhance doxorubicin toxicity

Background: Gastric cancer (GC) remains one of the leading causes of cancer-related death. Its aetiology is multifactorial, but the major risk factor is a high in salt diet. During gastric carcinogenesis, cadherin-1 (CDH1) down-expression and cyclooxygenase 2 (COX2) overexpression may be observed. T...

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Bibliographic Details
Main Authors: Agnieszka Korga, Marta Ostrowska, Magdalena Iwan, Małgorzata Skierucha, Aleksandra Józefczyk, Piotr Pawłowski, Jarosław Dudka, Ryszard Maciejewski, Robert Sitarz
Format: Article
Language:English
Published: Swedish Nutrition Foundation 2019-06-01
Series:Food & Nutrition Research
Subjects:
Garlic
Allium sp
gastric cancer
cyclooxygenase 2
E-cadherin
Online Access:https://foodandnutritionresearch.net/index.php/fnr/article/view/3449/9292

Internet

https://foodandnutritionresearch.net/index.php/fnr/article/view/3449/9292

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