Unique Polymorphisms at <i>BCL11A</i>, <i>HBS1L-MYB</i> and <i>HBB</i> Loci Associated with HbF in Kuwaiti Patients with Sickle Cell Disease

Unique Polymorphisms at <i>BCL11A</i>, <i>HBS1L-MYB</i> and <i>HBB</i> Loci Associated with HbF in Kuwaiti Patients with Sickle Cell Disease

Patients with sickle cell disease (SCD) in Kuwait have elevated HbF levels ranging from ~10–44%; however, the modulating factors are unclear. We investigated the association of single nucleotide polymorphisms (SNPs) at <i>BCL11A</i>, <i>HBS1L-MYB</i> and <i>HBB</i>...

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Bibliographic Details
Main Authors: Nagihan Akbulut-Jeradi, Maria Jinky Fernandez, Rasha Al Khaldi, Jalaja Sukumaran, Adekunle Adekile
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Journal of Personalized Medicine
Subjects:
sickle cell disease
HbF modifiers
genetic association
single nucleotide polymorphism
Kuwait
Online Access:https://www.mdpi.com/2075-4426/11/6/567

Internet

https://www.mdpi.com/2075-4426/11/6/567

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