The Staphylococcus aureus peptidoglycan protects mice against the pathogen and eradicates experimentally induced infection.

Staphylococcus aureus, in spite of antibiotics, is still a major human pathogen causing a wide range of infections. The present study describes the new vaccine A170PG, a peptidoglycan-based vaccine. In a mouse model of infection, A170PG protects mice against a lethal dose of S. aureus. Protection la...

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Bibliographic Details
Main Authors: Rosanna Capparelli, Nunzia Nocerino, Chiara Medaglia, Giuseppe Blaiotta, Patrizia Bonelli, Domenico Iannelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3228750?pdf=render