Ethyl 5-(4-Bromophenyl)-4-methyl-1H-pyrrole-2-carboxylate

This note describes a sequence converting an oxime-substituted pyrrolidine into a trisubstituted pyrrole structure. The synthetic route is based on a double chlorination of the pyrrolidine substrate followed by the base induced formation of both an imine and a nitrile oxide functionality. The latter...

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Bibliographic Details
Main Authors: Marcus Baumann, Ian R. Baxendale
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Molbank
Subjects:
Online Access:https://www.mdpi.com/1422-8599/2017/3/M951