Ethyl 5-(4-Bromophenyl)-4-methyl-1H-pyrrole-2-carboxylate
This note describes a sequence converting an oxime-substituted pyrrolidine into a trisubstituted pyrrole structure. The synthetic route is based on a double chlorination of the pyrrolidine substrate followed by the base induced formation of both an imine and a nitrile oxide functionality. The latter...
Main Authors: | Marcus Baumann, Ian R. Baxendale |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-08-01
|
Series: | Molbank |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-8599/2017/3/M951 |
Similar Items
-
Syn-Ethyl 1-hydroxy-7-methoxy-2,3-dihydro-1H-pyrrolo[3,4-b]quinolone-3-carboxylate HCl Salt
by: Marcus Baumann, et al.
Published: (2015-03-01) -
2-Amino-5-chloro-1<i>H</i>-pyrrole-3,4-dicarbonitrile
by: Andreas S. Kalogirou, et al.
Published: (2021-02-01) -
Lipid-Lowering Effects of Ethyl 2-Phenacyl-3-aryl-1H-pyrrole- 4-carboxylates in Rodents
by: Bruce S. Burnham, et al.
Published: (2004-02-01) -
Synthesis of 1-(4-Trifluoromethoxyphenyl)-2,5-dimethyl-3-(2-R-thiazol-4-yl)-1H-pyrroles via Chain Heterocyclization
by: Andrij O. Tolmachov, et al.
Published: (2010-02-01) -
Marine Pyrrole Alkaloids
by: Kevin Seipp, et al.
Published: (2021-09-01)