An evaluation of the anti-inflammatory properties of the pregnane X receptor gene isoforms PXR1 and PXR3
The pregnane X receptor (PXR) is a nuclear receptor (NR) that primarily activates genes involved in drug metabolism. However, PXR also suppresses inflammation. This study investigated the anti-inflammatory activity of PXR1 and the minor isoform PXR3. Luciferase reporter experiments showed that like...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2019-05-01
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| Series: | European Journal of Inflammation |
| Online Access: | https://doi.org/10.1177/2058739219848571 |