WP1130 reveals USP24 as a novel target in T-cell acute lymphoblastic leukemia

Abstract Background T-cell acute lymphoblastic leukemia (T-ALL) is a lymphoid malignancy caused by the oncogenic transformation of immature T-cell progenitors with poor outcomes. WP1130 has shown potent activity against a variety of cancer but whether WP1130 has anti-T-ALL activity is not clear. USP...

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Bibliographic Details
Main Authors: Hao Luo, Bo Jing, Yu Xia, Yugen Zhang, Meng Hu, Haiyan Cai, Yin Tong, Li Zhou, Li Yang, Junmei Yang, Hu Lei, Hanzhang Xu, Chuanxu Liu, Yingli Wu
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Cancer Cell International
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12935-019-0773-6