Bioengineering commensal bacteria-derived outer membrane vesicles for delivery of biologics to the gastrointestinal and respiratory tract

Bioengineering commensal bacteria-derived outer membrane vesicles for delivery of biologics to the gastrointestinal and respiratory tract

Gram-negative bacteria naturally produce and secrete nanosized outer membrane vesicles (OMVs). In the human gastrointestinal tract, OMVs produced by commensal Gram-negative bacteria can mediate interactions amongst host cells (including between epithelial cells and immune cells) and maintain microbi...

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Bibliographic Details
Main Authors: Ana L. Carvalho, Sonia Fonseca, Ariadna Miquel-Clopés, Kathryn Cross, Khoon-S. Kok, Udo Wegmann, Katherine Gil-Cardoso, Eleanor G. Bentley, Sanaria H.M. Al Katy, Janine L. Coombes, Anja Kipar, Regis Stentz, James P. Stewart, Simon R. Carding
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:Journal of Extracellular Vesicles
Subjects:
commensal bacteria
bacterial microvesicles
outer membrane vesicles
mucosal drug delivery
mucosal vaccines
therapeutic proteins
Online Access:http://dx.doi.org/10.1080/20013078.2019.1632100

Internet

http://dx.doi.org/10.1080/20013078.2019.1632100

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