Tumor Microenvironment-Induced Immunometabolic Reprogramming of Natural Killer Cells

Energy metabolism is key to the promotion of tumor growth, development, and metastasis. At the same time, cellular metabolism also mediates immune cell survival, proliferation and cytotoxic responses within the tumor microenvironment. The ability of natural killer cells to eradicate tumors relies on...

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Bibliographic Details
Main Authors: Andrea M. Chambers, Kyle B. Lupo, Sandro Matosevic
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02517/full