Motor cortical excitability predicts cognitive phenotypes in amyotrophic lateral sclerosis

Motor cortical excitability predicts cognitive phenotypes in amyotrophic lateral sclerosis

Abstract Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are well-recognised as an extended disease spectrum. This study hypothesised that cortical hyperexcitability, an early pathophysiological abnormality in ALS, would distinguish cognitive phenotypes, as a surrogate marker o...

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Bibliographic Details
Main Authors: Smriti Agarwal, Elizabeth Highton-Williamson, Jashelle Caga, James Howells, Thanuja Dharmadasa, José M. Matamala, Yan Ma, Kazumoto Shibuya, John R. Hodges, Rebekah M. Ahmed, Steve Vucic, Matthew C. Kiernan
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81612-x

Internet

https://doi.org/10.1038/s41598-021-81612-x

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